Tuesday publication post! 📖 Have you ever wondered how radiolysis affects highly sensitive materials in different liquids? In this publication, the #PoseidonAX system enabled a systematic investigation of electron beam damage in the metal-organic framework (MOF) ZIF-8 during liquid cell transmission electron microscopy (#LCTEM). By combining in situ imaging, electron diffraction, and postmortem 4D-STEM analysis, the authors reveal how imaging conditions influence both the morphology and crystallinity of this highly beam-sensitive material.
Key highlights:
💧 Poseidon AX enabled in situ LCTEM studies of ZIF-8 in different liquid environments, revealing significantly greater morphological stability in dimethylformamide (DMF) compared to water
⚡ The study establishes that ZIF-8 crystallinity is primarily governed by accumulated electron fluence, with loss of crystallinity occurring at a critical dose of approximately 80 e⁻ Å⁻² regardless of solvent environment
🗺️ Postmortem 4D-STEM analysis revealed electron beam damage extending beyond the directly imaged region and demonstrated that radiolytic effects are more pronounced during TEM imaging than STEM imaging
This work provides important insights into the mechanisms of electron beam-induced damage in metal-organic frameworks during liquid-phase electron microscopy. The findings establish practical guidelines for evaluating radiolysis effects and optimizing imaging conditions, helping researchers obtain more reliable nanoscale observations of beam-sensitive materials in liquid environments.
Want to read the entire work? Find it here! https://www.doi.org/10.1021/acs.nanolett.4c02242
Want to know more about our Poseidon AX system?
#FindYourBreakthrough #LiquidCellMicroscopy #InSituTEM #InSituLiquid #InSituMicroscopy #Protochips
